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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Folic acid leads to the methylation of TP53. 2 / 2

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"These data indicate that secreted FOLR3 could induce p53 methylation by efficient folic acid uptake and affect the cell viability of SH-SY5Y cells.Endocytosis involves the process of transporting molecules into the cell by engulfing it with its membrane."

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"In contrast, folic acid metabolizes homocysteine to methionine and induces p53 DNA methylation, supressing Hcy-induced toxicity ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...