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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

IL6 increases the amount of IGF1R. 2 / 2

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"In addition, IL-6 treatment induced IGF-1 secretion and IGF-1R expression in NANOG and OCT4-HCC cell lines in a dose dependent manner [XREF_BIBR], suggesting crosstalk between IL-6 and STAT3 signaling and IGF and IGF-1R signaling in HCC cancer stem cells (XREF_FIG)."

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"However, the protein expressions of thyroid-stimulating hormone receptor and insulin-like growth factor 1 receptor could not be directly increased by IL-6/sIL-6R stimulation in CD34+ OFs."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...