IndraLab

Statements

TRH activates STAMBP. 20 / 20
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"However, the present study indicates that SRIF does not modulate TRH induced aMSH release by frog neurointermediate lobes."
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"Several recent studies have demonstrated that in the frog, the tripeptide pGlu-His-Pro-NH2 (mammalian TRH) specifically stimulates a-MSH release by NIL in vitro (Vaudry et al., 1977; Tonon et al., 198[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Our results suggest that extracellular prostaglandins may modulate the release of a-MSH induced by TRH which indicate that prostaglandins act on mammalian thyrotroph and amphibian melanotroph receptor[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"As shown in Fig. 3, SRIF (10 -6 M) was unable to alter either spontaneous oMSH release or TRH induced a-MSH secretion by the NIL."
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"At doses of 10-8 and 10-6 M, synthetic somatostatin did not modify TRH induced a-MSH secretion."
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"2) Infusion of indomethacin alone (5 x 10-6M) did not alter the spontaneous release of a-MSH; 3) Association of indomethacin and TRH did not modify TRH stimulated a-MSH release; 4) Although a-MSH rele[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Conversely a significant increase in TRH induced a-MSH secretion was observed in the presence of 1 x 10-6M PGE1."
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"In the present study, the effects of various neuropeptides on spontaneous and/or TRH induced a-MSH secretion were investigated, using a well defined perifusion system technique."
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"Thus, the model of SRIF action proposed by these authors, together with our results showing the lack of action of SRIF upon TRH induced a-MSH release, makes it improbable that, in the frog NIL, TRH ac[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"No alteration of TRH induced a-MSH release was observed in the presence of a 100-fold excess of Tyr MIFI."
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"r. h, ~ (n p a r a z v 0 z h PROSTAGLANDINS C C% ~ 6 LV.5 4 W 02 TRH concentration 10-8 10 7 n n 10 ' 6 n;, j;,, 's 0 11 ' e, kl " 1 1 2 3 4 5 hours Figure 3 : Effect of PGE1 on TRH induced a-MSH rele[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"This elegant immunohistochemical study together with our demonstration that TRH stimulates a-MSH secretion in vitro strongly suggests that, in anurans, TRH is a physiological regulator of the intermed[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Since it was previously demonstrated that PGEs potentiate the stimulatory effect of TRH on TSH release in vivo (19) and in vitro (14, 16), it was decided to investigate the possible regulatory roles o[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"They also demonstrate that these peptides do not modify TRH induced a-MSH release."
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"Indomethacin did not alter the a-MSH release induced by TRH."
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"Our data show that PGE1 potentiates the release of a-MSH induced by TRH."
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"Since in our model indomethacin does not blunt the release of a-MSH induced by TRH, the present data show that endogenous prostaglandins are not involved in the response of intermediate lobe pituitary[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"For doses ranging from 10 -9 to 10-6M, VIP did not significantly alter a-MSH secretion whereas TRH induced a marked increase in (x-MSH release with half-maximum stimulation (EDSO) at 1.2 x 10-8M Table[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In addition, prolonged infusion of T, in vitro did not alter spontaneous and TRH induced a-MSH release."
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"In spite of the inhibitory effect of T, on TRH induced TSH and prolactin secretions in mammals, the present data show that, in frogs, thyroid hormone does not modulate the stimulation of a-MSH secreti[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
6414878