Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Phosphorylated MTOR activates SRC. 1 / 1

| 1

➶

reach

"In poor prognosis patients with RMS (that is, those with advanced or metastatic disease), IRS-1 activation appears refractory to normal negative feedback mediated by increased phosphorylated mTOR and S6 Kinase 88, and inhibiting IGF1R activity can promote compensatory regulatory activity of the SRC family kinase, YES 89."

30617281

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...