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WP1130 activates UCHL5. 1 / 1

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"It has been previously reported that WP1130 targets the deubiquitinases (DUBs) USP5, USP9X, USP14, UCHL1 and UCHL5.27 In order to test whether these DUBs are involved in the regulation of ULK1 expression levels, we transfected HEK293 cells simultaneously with the corresponding siRNAs and analyzed endogenous ULK1 expression after 48 and 72 h, respectively However, we could not detect any alterations of ULK1 expression levels."

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IndraLab

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WP1130 activates UCHL5. 1 / 1

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