IndraLab

Statements

BAP1 increases the amount of BAP1. 5 / 5
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"Genetic mutations in BAP1 could modulate BAP1 protein expression or could alter BAP1 function in the absence of alterations in protein expression."
28122578
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"Deletion of chromosome 3 and BAP1 inactivating mutations cause loss of BAP1 expression and function in cancer."
33208912
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"BAP1-IP3R3 CoIP was barely detectable in BAP1 +/- fibroblasts; BAP1 rescue significantly increased the amount of BAP1 that CoIP with IP3R3 (XREF_FIG)."
28614305
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"We also detect the mRNA and protein expression level of BAP1, tumors with BAP1 plasmid transfected group exhibited higher BAP1 mRNA and protein expression compared with the control group, suggesting that BAP1 plasmid overexpression could rescue the expression of BAP1 suppressed by miR-31."
29159179
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"Mechanically, we show that BAP1 represses metabolic stress induced UPR and cell death through activating transcription factor 3 (ATF3) and C/EBP homologous protein (CHOP), and reveal that BAP1 binds to ATF3 and CHOP promoters and inhibits their transcription."
28275095