IndraLab

Statements

CDK4 binds CCND1, RB1, and CDK6. 3 / 3
1 | 2
sparser
"We found that high expression of CDK4, CDK6, CCND1, and phospho-RB1 was associated with higher proliferative index, as defined by MKI67."
28991877
hprd
No evidence text available
9380698
sparser
"As a key mediator of cell cycle progression, cyclin D1 forms complex with cyclin-dependent kinase 4 (CDK4) and CDK6 to inactivate the retinoblastoma (RB) pathway via hyperphosphorylation of the RB protein and result in acceleration of E2F-mediated gene transcription xref ."
28602785