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PSMD14 binds SNAIL. 3 / 3

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"Mechanically, THL impaired the interaction between PSMD14 and SNAIL, then promoted the ubiquitination and degradation of SNAIL to inhibit EMT which plays a crucial role in ESCC metastasis, stemness and chemosensitivity."

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"THL weakens the interaction between PSMD14 and SNAIL to accelerate the degradation of SNAIL."

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"Furthermore, co-immunoprecipitation assay was conducted to test the impact of THL on the interaction between PSMD14 and SNAIL in ESCC cells."

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IndraLab

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PSMD14 binds SNAIL. 3 / 3

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