IndraLab

Statements

Dihydroartemisinin binds KCNMA1. 4 / 4
| 1 3
sparser
"This indicates that DHA may interact with KCa1.1 [ xref , xref ] and/or K 2P channels [ xref ] directly in the smooth muscle layers and is not strictly dependent on endothelial function to cause vasorelaxation."
23724868
reach
"This indicates that DHA may interact with KCa1.1 [XREF_BIBR, XREF_BIBR] and/or K 2P channels [XREF_BIBR] directly in the smooth muscle layers and is not strictly dependent on endothelial function to cause vasorelaxation."
23724868
sparser
"When DHA is applied to Slo1 BK channels without heterologously expressed auxiliary subunits, a small current-enhancing effect of DHA is observed, strongly indicating that the presence of β1 or β4 potentiates the functional consequence of DHA binding to the Slo1 subunit ( xref )."
24127525
sparser
"The results are collectively consistent with the idea that the functional consequence of the interaction of DHA with the Slo1 protein is amplified by the presence of β1 ( xref )."
24127525