IndraLab
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"Furthermore, miR-125b target genes (histone methyltransferase Suv39h1 and the NF-kappaB negative regulator TNFAIP3 [tumor necrosis factor alpha induced protein 3]) were downregulated, which resulted in increased proinflammatory cytokine expression, aortic macrophage recruitment, MMP (matrix metalloproteinase)-2/9 activity, elastin fragmentation, and vascular smooth muscle cell loss in ATP7A mut/+ / ApoE -/- mice and reversed by locked nucleic acid-anti-miR-125b infusion."