A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

IndraLab

Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
reading

TSC1 binds TSC2 and proline. 1 / 1
| 1
reach
"Perhaps the most dramatic metabolic consequence of PI3K and Akt stimulation however, is downstream activation of the cell growth regulator mechanistic target of rapamycin complex 1 (mTORC1) upon Akt mediated phosphorylation of either of two mTORC1 inhibitors : tuberous sclerosis 2 (TSC2; part of the TSC1 and TSC2 complex) or proline rich Akt substrate 40 kDa (PRAS40)."