IndraLab

Statements

KCNMA1 activates lipopolysaccharide. 5 / 5
| 5
reach
"Here, using patch clamping, Griess reaction, ELISA, immunocytochemistry and immunoblotting approaches, we show that specific inhibition of the BK channel with paxilline (10 muM) or siRNA mediated knockdown of its expression significantly suppresses lipopolysaccharide (LPS)-induced (100 ng/ml) BV-2 and primary mouse microglial cell activation."
31296663
reach
"Vascular BK channel deficiency shortened the latency to mortality and increased the mortality rate not only in LPS induced sepsis, but also in CLP induced sepsis."
21997262
reach
"LPS activated, adherent peritoneal macrophages were treated with rMuGzmA and sublytic SLO or with ATP for 3 hr."
18951048
reach
"Here, using patch clamping, Griess reaction, ELISA, immunocytochemistry and immunoblotting approaches, we show that specific inhibition of the BK channel with paxilline (10 muM) or siRNA mediated knockdown of its expression significantly suppresses lipopolysaccharide (LPS)-induced (100 ng/ml) BV-2 and primary mouse microglial cell activation."
31296663
reach
"BK channel activity as NPo increased 3-fold within 30 min exposure to LPS."
29466671