IndraLab

Statements


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reach
"Subsequent co-immunoprecipitation (Co-IP) experiments demonstrated an interaction between USP14 and vimentin in GC lines."

sparser
"These results demonstrated that BECN1 affected the ubiquitination of Vimentin through regulating the interaction between USP14 and Vimentin."

sparser
"For instance, in human gastric cancer cell lines, the deubiquitinating enzyme USP14 directly interacts with vimentin and stabilizes it through deubiquitination (Zhu et al., 2017)."

sparser
"In this study, we further verified the high expression levels of USP14 in GC cell lines and tissues and found that USP14 interacts with vimentin, de-ubiquitinates it, and increases its expression level in GC cells, which promotes cell aggressiveness, including the growth, migration and invasion of gastric cancer cells."

No evidence text available

sparser
"Subsequent co-immunoprecipitation (Co-IP) experiments demonstrated an interaction between USP14 and vimentin in GC lines (Figure xref and xref )."

reach
"Furthermore, we explored the mechanism of the aberrant expression of vimentin and found that USP14 interacts with vimentin and de-ubiquitinates it."

reach
"In this study, we further verified the high expression levels of USP14 in GC cell lines and tissues and found that USP14 interacts with vimentin, de-ubiquitinates it, and increases its expression level in GC cells, which promotes cell aggressiveness, including the growth, migration and invasion of gastric cancer cells."

No evidence text available

sparser
"Furthermore, we explored the mechanism of the aberrant expression of vimentin and found that USP14 interacts with vimentin and de-ubiquitinates it."