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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

UCHL1 deubiquitinates MHC I. 46 Another DUB. 1 / 1

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"Ubiquitin C-terminal hydrolase-L1 (UCH-L1) has been shown to positively regulate MHC I recycling and antigen cross presentation to CD8 T cells, although it is unclear whether UCH-L1 directly deubiquitinates MHC I. 46 Another DUB, USP14, facilitates MHC I restricted direct antigen presentation, particularly the peptides derived from defective ribosomal products (DRiPs)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...