IndraLab

Statements


USP25 deubiquitinates RPS20. 4 / 4
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"Taken together, these results indicate that USP21 or OTUD3 can deubiquitylate both eS10 and uS10, resulting in enhanced readthrough of poly(A)-mediated stall events."

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"USP21 and OTUD3 antagonize the ubiquitination of eS10 and uS10 that results from integrated stress response (ISR) and ribosome-associated quality control pathway (RQC) (124)."

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"Exogenous expression of USP21 substantially reduced the ZNF598-stimulated eS10 and uS10 ubiquitylation in an activity-dependent manner (Figure 3E)."

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"USP21 and OTUD3 deubiquitylate ZNF598 substrates eS10 and uS10."