IndraLab

Statements

PPP2CA dephosphorylates AKT1 on T308. 5 / 5
2 3 |
hprd
No evidence text available
12637511
signor
"Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes"
15367694
hprd
No evidence text available
12637511
hprd
No evidence text available
12637511
signor
"Overexpression of BTBD10 increased phosphorylation levels of Akts at both Thr(308) and Ser(473) while the reduction of the endogenous BTBD10 level resulted in a decrease in the phosphorylation levels of Akts. In vitro analysis indicated that BTBD10 bound to protein phosphatase 2A (PP2A) and inhibited dephosphorylation of Akts by PP2A."
18160256