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EGF leads to the phosphorylation of IRS1 on S307. 2 / 2
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"Taken together, these results demonstrated that the serine 307 phosphorylation of IRS-1 induced by EGF and FGF is mediated by a PI 3-kinase-dependent but a PKD1 independent signaling pathway.Knowledge[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"As shown in Fig. 9 A, EGF and FGF strongly stimulated the phosphorylation of IRS-1 on serine 307."