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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP7 activates PYCARD. 2 / 2

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"In this study, we demonstrated that inhibition of protein deubiquitinase USP7 suppressed osteogenic differentiation of hASCs in a catalytic activity dependent manner, while overexpression of USP7 enhanced hASC osteogenesis."

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"Another study found that pharmacological inhibition of USP7 and USP47 prevented the formation of ASC specks and dramatically decreased both IL-18 and IL-1beta release."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...