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CDK4-R24C leads to the phosphorylation of RB1. 1 / 1

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"Exogenous expression of an R24C mutant of CDK4, which cannot be bound by the p16INK4A protein and cyclin D1 therefore induces constitutive activation of the cyclin D-CDK4 complex, and induces pRB phosphorylation, resulting in escape from premature senescence."

34059723

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IndraLab

Statements

CDK4-R24C leads to the phosphorylation of RB1. 1 / 1

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