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"An increase in fasting insulin levels and glucose stimulated insulin levels during GH treatment has been previously reported in children with short stature born SGA who received long-term GH treatment, suggesting that relative insulin resistance may develop during long-term GH treatment."
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"In contrast, serum insulin levels increased during the first treatment year in all groups, resulting in a more marked elevation of integrated insulin levels in transplant (1402 +/- 179 pM) and dialysis (1025 +/- 114 pM) patients compared with conservatively treated patients (829 +/- 94 pM), and control subjects (719 +/- 89 pM) (p < 0.01)."