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OTUD7B inhibits LCL161-induced NF-kappaB pathway. 1 / 1

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"* P < 0.05 OTUD7B deubiquitinates TRAF3 to inhibit NIK To examine the potential mechanism by which OTUD7B inhibits the LCL161-induced NF-kappaB pathway , we transfected Flag-TRAF3 and HA-OTUD7B , Myc-NIK and HA-OTUD7B into H1299 cells for 48 h. Reciprocal co-immunoprecipitation was performed using anti-Flag anti-Myc and anti-HA antibodies to confirm whether OTUD7B directly binds to NIK or TRAF3 ."

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OTUD7B inhibits LCL161-induced NF-kappaB pathway. 1 / 1

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