IndraLab

Statements


NRAS activates mutated KRAS. 3 / 3
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"Another study highlighted the importance of wild-type RAS proteins by revealing that wild-type HRAS and NRAS promote mutant KRAS driven tumorigenesis XREF_BIBR."

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"Wild-type H- and N-Ras promote mutant K-Ras driven tumorigenesis by modulating the DNA damage response."

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"Deletion of Hras or Nras increased the number of mutant Kras driven lung tumors, suggesting that Hras and Nras attenuate the ability of mutant Kras to promote lung carcinogenesis."