IndraLab

Statements

EIF3F activates Death. 2 / 2
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"The same effect was reached in colorectal carcinoma cells lacking of p53 (HCT116 p53 -/-) in about 1 hour for MD 11 -K510R, 1.5 hours for MD 11 -NF and 3 hours for MD 11 -wt eIF3f, confirming that this cell line is more resistant than wild-type to the death stimulus and that p53 may play a role in eIF3f induced death (XREF_FIG)."
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reach
"For instance, one hour treatment of MD 11 -wt eIF3f induced 30% death in Colo857 and HCT116 p53 -/- and 50% in B16 and HCT116 p53 +/+, while MD 11 -K510R killed as expected 50% of Colo857 cells and 100% of the others."
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