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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

BRCC3 binds phosphorylated ABRAXAS1. 1 / 1

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"BRCA1 binds with its BRCT domain to phosphorylated ABRA1, which acts as a scaffold and binds BRCC36 (BRCA1 and BRCA2 containing complex subunit 36, also known as BRCC3), a deubiquitinating enzyme, BRCC45 (BRCA1 and BRCA2 containing complex subunit 45, also known as BRE), and RAP80, which is essential for the recruitment of BRCA1."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...