IndraLab

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ATXN3 activates DHX40. 2 / 2
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"Notably, a smaller amount of ubiquitinated proteins was coprecipitated with p97 from cells expressing wt atx3 (XREF_FIG, lane 5 vs. lane 1; XREF_FIG, lane 3 vs. lane 1), suggesting that atx3 mediated PAD may also occur in intact cells."

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"Together, these data suggest that atx3 can promote PAD both in intact cells and in vitro."