IndraLab

Statements

Phosphorylated ELK1 is transcriptionally active. 4 / 4
4 |
bel
"This approach revealed a previously unrecognized transcriptional target of ELK-1, the human tissue plasminogen activator (tPA)."
15590693
bel
"MSK1 induction requires simultaneous activation of both ERK and p38 MAPK. Other downstream targets of p38 MAPK include transcription factors such as Elk1 and myocyte-enhancing factor (MEF) 2, whereby p38 MAPK directly phosphorylates nuclear substrates and augments their activity (Chen et al. 2001)."
15294035
bel
"Elk-1-dependent transactivation is regulated by phosphorylation at serine-383 and -389, and each of the MAPK has been shown to be competent to phosphorylate this nuclear factor at these residues in vitro (33, 34, 35, 36, 37)."
11441089
bel
"RIP2 directly phosphorylates and activates ERK2 in vivo and in vitro."
10559258