IndraLab
Statements
Pyraclofos activates HCN1. 14 / 14
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"When expressing a phosphomimetic mutant that is analogous to constitutively phosphorylated S791 (rat HCN1-S791D) in Xenopus oocytes, we observed a hyperpolarizing shift in HCN1 channel voltage-dependent activation, similar to that seen in our rat model of acquired epilepsy ( xref ; xref )."