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USP39 binds ADAM9. 2 / 2
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"Furthermore, to determine whether USP39 could interact with ADAM9 and regulate the ubiquitination of ADAM9, we co‐transfected Myc‐tagged USP39, Flag‐tagged ADAM9 with or without HA tagged Ub plasmids into HEK293T cells; co‐immunoprecipitation experiments revealed that USP39 failed to interact with ADAM9 at the protein level (Fig.  xref ) and overexpressing USP39 had no effect on the polyubiquitination of ADAM9 (Fig. S9B)."
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"Interestingly, Xiao et al. found that USP39 also directly binds to ADAM9 mRNA and promotes its pre-mRNA maturation, thereby altering the expression and activity of integrin β1 and promoting migration and invasion of human glioma cells ( xref )."
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