IndraLab

Statements

PSMD14 leads to the deubiquitination of SMAD3. 3 / 3
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"Moreover, stable knockdown of POH1 in H1299 cells enhanced endogenous Smad3 ubiquitination ( Fig. 4 C)."
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"In this study, we demonstrated that POH1 abolished the polyubiquitination of Smad3 but not phosphorylated Smad3."
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"Thus, POH1 reduced the overall ubiquitination of Smad3 by cutting off the basal part of the k63/k48 branching chain, as shown in Fig. 4 F."
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