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Modified USP8 leads to the ubiquitination of FLIP. 1 / 1

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"Over-expression of WT USP8, but not catalytically inactive USP8, increased FLIP S ubiquitination, decreased FLIP S half-life, decreased FLIP S steady-state levels, and decreased TRAIL resistance, while siRNA mediated suppression of USP8 levels had the opposite effects."

20484045

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IndraLab

Statements

Modified USP8 leads to the ubiquitination of FLIP. 1 / 1

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