IndraLab

Statements

BRAF binds PBK and KRAS. 3 / 3
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"As a MAPKK-like protein, it is a downstream molecule of KRAS and BRAF , both of which are associated with diffuse expression of TOPK ( xref )."
19935791
sparser
"Molecular analysis of sporadic CRCs in Group 2 showed that diffuse TOPK expression was associated with KRAS and BRAF mutations (p<0.001) and with poor outcome in patients with either mutation in univariate and multivariate analysis ( P =0.017)."
19935791
sparser
"In sporadic CRC, diffuse TOPK expression was associated with the presence of KRAS or BRAF mutation, underlining the involvement of TOPK in ERK/MAPK signalling."
19935791