IndraLab

Statements

AMPK inhibits KCNA5. 3 / 4
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eidos
"By contrast , the expression of Kv1.5 , which is inhibited rather than activated by AMPK [ 39,50 ] , appears to be restricted to the caudate putamen , the granule layer of the cerebellum , trigeminal sensory ganglia , pituitary gland and olfactory system ( olfactory bulb , trigeminal terminal nerves and nasal vomeronasal organ ) [ 97,98,99 ] ."
32429235
reach
"By contrast, however, intracellular dialysis of AMPK heterotrimers containing either AMPK-α1 or AMPK-α2 inhibited KV1.5 in rat pulmonary arterial myocytes [39], adding further weight to the argument that target specificity is determined by the anchoring of endogenous AMPK heterotrimers proximal to their targets, rather than by the intrinsic target specificity of any given subunit combination."
32429235
sparser
"AMPK inhibits Kv1.5 presumably in part by activation of Nedd4- 2 with subsequent clearance of channel protein from the cell membrane."
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