IndraLab

Statements

INSR decreases the amount of IRS1. 3 / 24
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"This study showed that (i) the expression of miR-1271 in hepatocytes is upregulated by palmitate; (ii) miR-1271 targets INSR and IRS-1 3 ' UTRs directly and downregulates the expression of INSR and IR[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
27613089
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"Therefore, we further revealed that miR-96 targets 3 ' UTRs of INSR and IRS-1 genes directly to suppress the expression of the INSR and IRS-1 protein, resulting in impaired insulin signaling and glycogen synthesis."
28036389
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"Both insulin receptor substrate 1 and 2 (IRS-1 and IRS-2) expression are decreased in the obese Zucker rat and, as a result, there is decreased IRS phosphorylation by activated insulin receptor kinase[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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