IndraLab

Statements

Kinase-active AKT leads to the phosphorylation of GSK3. 1 / 1
1 |
bel
"Stable transfection of H1299 NSCLC cells with Akt(DD), another constitutively active form of Akt, stimulated Akt-dependent signalling, as shown by increased expression of P-GSK3 (phosphorylated GSK3) (Figure 1C), and suppressed RA-induced RARB expression (Figure 1D). Together, these findings indicate that activation of Akt inhibits ligand-dependent activation of retinoid receptors."
16417524