IndraLab

Statements

PSMD14 binds AGR2. 5 / 5
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"To verify that PSMD14 regulated AGR2 through deubiquitination, we performed endogenous and exogenous Co-IP experiments and confirmed that PSMD14 directly binds to AGR2 protein."
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"For example, further rigorous verification of the interaction between PSMD14 and AGR2 protein is needed, as well as site-binding verification of PSMD14 with AGR2 protein."
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"We then used Co-IP to confirm the interaction between PSMD14 and AGR2 proteins in different cell lines."
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"We first transfected HEK-293T cells with HA-PSMD14 and Myc-AGR2 plasmids and performed exogenous Co-IP using anti-HA tag antibody. xref shows that Myc tag protein was detected in Co-IP samples, indicating that PSMD14 directly binds to AGR2 protein."
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sparser
"These results demonstrated that PSMD14 interacted with AGR2 protein in LUAD cells."
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