IndraLab

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EIF3F inhibits rRNA catabolic process. 2 / 2
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"Mechanistically, the authors found that eIF3f inhibits both cap-dependent and cap-independent translation and that eIF3f promotes rRNA degradation through direct interaction with heterogeneous nuclear ribonucleoprotein K (Wen et al., 2012)."
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"Furthermore, one mechanism of translation inhibition likely involves eIF3f-mediated rRNA degradation by a direct eIF3f-hnRNP K (RNA-binding protein) interaction [109]."
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