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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

EIF3F inhibits rRNA catabolic process. 2 / 2

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"Mechanistically, the authors found that eIF3f inhibits both cap-dependent and cap-independent translation and that eIF3f promotes rRNA degradation through direct interaction with heterogeneous nuclear ribonucleoprotein K (Wen et al., 2012)."

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"Furthermore, one mechanism of translation inhibition likely involves eIF3f-mediated rRNA degradation by a direct eIF3f-hnRNP K (RNA-binding protein) interaction [109]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...