IndraLab

Statements



sparser
"Although difficult to assess quantitatively, the efficiency with which recombinant Rheb associates with HA-mTOR in vivo or in vitro appears to be low."

sparser
"Thus, although the nucleotide-deficient Rheb mutants bind HA-mTOR more tightly than does wild-type Rheb, the HA-mTOR polypeptides bound to these mutants are unable to acquire kinase activity during tr[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

sparser
"We infer that HA-mTORs bound to wild-type Rheb reflect a mixture of HA-mTORs bound to Rheb-GTP, which have high kinase activity, and (given the 40%–50% GDP charging we observe for wild-type Rheb) a co[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"