IndraLab

Statements


Glu-Ala activates CYLD. 3 / 3
| 3

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"EA upregulated CYLD mRNA and protein expression in the peri-ischemic cortex after ischemia and reperfusion but EA caused a substantial drop in CYLD protein at 6 h reperfusion."

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"CYLD silencing partially weakens anti-inflammatory effects of EA so EA may repress excessive activation of microglia and reduce deleterious pro inflammatory cytokines in part by upregulating CYLD after focal cerebral ischemia and reperfusion."

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"In addition, EA increased the number of neuronal CYLD positive cells in the ischemic cortical border region at 24 h reperfusion."