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Ubiquitin inhibits UCHL3. 10 / 11
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"As an additional control experiment, we measured a Ki of 0.27 μM for the inhibition of UCH-L3 by ubiquitin with the substrate ubiquitin-AMC."
16905103
sparser
"As an additional control experiment, we measured a K of 0.27 μM for the inhibition of UCH-L3 by ubiquitin with the substrate ubiquitin-AMC."
16905103
sparser
"As an additional control experiment, we measured a Ki of 0.27 μM for the inhibition of UCH-L3 by ubiquitin with the substrate ubiquitin-AMC."
16905103
reach
"The present data demonstrated that ubiquitin aldehyde can inhibit the activity of UCHL3."
27780264
eidos
"As an additional control experiment , we measured a K i of 0.27 mM for the inhibition of UCH-L3 by ubiquitin with the substrate ubiquitin-AMC ."
16905103
reach
"As an additional control experiment, we measured a K i of 0.27 mM for the inhibition of UCH-L3 by ubiquitin with the substrate ubiquitin-AMC."
16905103
reach
"As an additional control experiment, we measured a K i of 0.27 muM for the inhibition of UCH-L3 by ubiquitin with the substrate ubiquitin-AMC."
16905103
sparser
"Using our Ub tools to profile UCHL3's activity, we generate a quantitative kinetic model of the inhibitory mechanism and we find that K27 Ub 2 can inhibit UCHL3 covalently, by binding to its catalytic cysteine, and allosterically, by locking its catalytic loop tightly in place."
33238157
sparser
"As an additional control experiment, we measured a K i of 0.27 mM for the inhibition of UCH-L3 by ubiquitin with the substrate ubiquitin-AMC."
16905103
reach
"(2) The kinetics of inhibition of UCH-L3 by ubiquitin C-terminal aldehyde (Ub-H) were determined and reveal a Ki that is less than 10 (-14) M. Several mechanisms are considered to account for the extreme inhibition."
9485312