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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

PSMD10 decreases the amount of TSC2. 2 / 2

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"Gankyrin knockdown dramatically increased TSC2 protein levels while decreasing mTORC1 signaling (P-S6K1)."

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"Furthermore, gankyrin knockdown inhibited oncogenic growth (growth curve and Ki67 staining) of DLD1, HCT116 and SW480 xenograft tumors in nude mice, and restored TSC2 expression while attenuating mTOR[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...