IndraLab

Statements


OTUB1 increases the amount of MAPT. 4 / 4
2 | 2

"Otub1 also significantly increased total Tau protein level compared with GFP control (Fig. 3b)."

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"Otub1 also significantly increased total Tau protein level compared with GFP control."

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"OTUB1 also increases the expression level of Tau, and the degradation of Tau is also impaired when the expression of OTUB1 is suppressed."

"We found that Tau degradation was significantly impaired in primary neurons infected with Otub1 WT, but not with catalytically dead mutant C91A, compared with GFP control."