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"Yod1, which is specifically associated with macro-autophagy, and codes for the cofactor YOD1, which binds with p97 to promote lysosomal clearance (Papadopoulos et al., 2017), was significantly increased in the FMD 3xTg male cohort compared with male 3xTg controls, although this effect was not observed in female 3xTg mice (Table S1; Data S1, page 47)."