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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP1 activates TP53BP1. 1 / 1

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"To our interest, USP1 reportedly destroys K63 linked polyubiquitin chains on histones and then promotes to recruit 53BP1 at DNA damage sites; another previous report found that KDM4A regulates DNA repair by controlling the recruitment of 53BP1 at DNA damage sites and RNF8 dependent degradation of KDM4A regulates DNA repair by controlling the recruitment of 53BP1 at DNA damage sites."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...