IndraLab

Statements

KCNMA1 increases the amount of IL1B. 4 / 4
| 4
reach
"Although alpha toxin was shown to induce a strong proinflammatory response from the cells, SLO only induced a low level of IL-1beta."
19201891
reach
"In contrast, SLO and PFO induced similar secretion of pro-IL-1β and IL-1β from GSDMD-KO iBMDMs with or without cell death (Fig. 4i, j), like in the liposome experiments (Fig. 3k, Extended Data Fig. 8l, m)."
33883744
reach
"Under a sub-lytic condition (lack of bulky 2 MDa dextran release from liposomes), SLO and PFO did not induce preferential release of mature IL-1β (Fig. 3k, Extended Data Fig. 8l, m)."
33883744
reach
"In contrast to the proinflammatory response to alpha toxin from the HVECs, SLO alone (10 mug/ml) induced only a low level of IL-1beta from the cells (XREF_FIG)."
19201891