IndraLab

Statements

Ibogaine inhibits KCNH2. 3 / 3
| 3
sparser
"Preliminary experiments in our laboratory do in fact suggest that also hERG channel inhibition by ibogaine is reinforced under low external potassium (unpublished data)."
25642835
sparser
"This observation goes along with noribogaine’s inhibitory action on hERG potassium channels (IC 50  = 3 µM: Fig.  xref ; [ xref ]), which very closely resembles hERG inhibition by ibogaine [ xref , xref , xref ]."
27020671
sparser
"The concentration-dependence of hERG channel inhibition by ibogaine and 18-MC was determined as in our previous study ( xref ) by the pulse protocol shown in xref a, applied at a frequency of 1 Hz."
23707769