IndraLab

Statements



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"Inhibition of UCH-L1 by LDN Leads to MT Reorganization and Stabilization in Oligodendroglial Cells."

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"The mechanism(s) by which inhibition of UCH-L1 by LDN affects its interaction with the members of autophagy pathway are unknown."

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"In vitro studies verified the LDN-induced inhibition of UCH-L1 had minimal effect on LC3 (a marker of autophagy) in control cells, in cells over expressing a-syn UCH-L1 inhibition resulted in increased LC3 activity."

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"To demonstrate the efficacy of UCH-L1 inhibition by LDN, neuronal lysates were pre-incubated with increasing amounts of LDN prior to DUB labeling assays."