IndraLab

Statements

AKT phosphorylates GATA1 on S310. 10 / 11
1 1 | 3 5
sparser
"It has been reported that Akt directly phosphorylated GATA1 at serine 310 [ xref ], and PAK5 was in higher expression in breast cancer tissues than matched adjacent noncancerous tissues."
25726523
signor
"We found that akt directly phosphorylates the transcription factor gata-1 at serine 310 and that this site-specific phosphorylation is required for the transcriptional activation of the timp-1 promoter."
16107690
reach
"It has also been reported that Akt dependent phosphorylation of GATA-1 at serine 310 is necessary for EPO induced erythrocyte terminal differentiation in a proerythroblast cell line XREF_BIBR and for EPO induced TIMP1 secretion and maturation of fetal liver erythroid cells XREF_BIBR."
23717580
sparser
"AKT serine threonine kinase phosphorylates GATA-1S310 in vitro and in erythroid cells and enhances GATA-1 transcriptional activity."
16204311
reach
"AKT phosphorylates GATA-1 at Ser 310 and enhances its transcriptional activity in primary fetal liver cells (42)."
18469073
phosphoelm
No evidence text available
16107690
sparser
"AKT phosphorylates GATA-1 at Ser-310 and enhances its transcriptional activity in primary fetal liver cells (42) ."
18469073
reach
"Here, we show that erythropoietin activates AKT, which phosphorylates GATA-1 at Ser310, thereby increasing GATA-1 affinity for FOG-1."
26680303
sparser
"It has also been reported that Akt-dependent phosphorylation of GATA-1 at serine 310 is necessary for EPO-induced erythrocyte terminal differentiation in a proerythroblast cell line xref and for EPO-induced TIMP1 secretion and maturation of fetal liver erythroid cells xref ."
23717580
sparser
"Here, we show that erythropoietin activates AKT, which phosphorylates GATA-1 at Ser310, thereby increasing GATA-1 affinity for FOG-1."
26680303