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PRPF8 activates PR degeneration humans. 1 / 1
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"Due to the high percentage of alternatively spliced genes in the human retina [ 412,413 ] , it is not surprising that mutations in mRNA splicing genes : PRPF3 , PRPF4 , PRPF6 , PRPF8 , PRPF31 , PDAP1 , and BNC2 have been shown to lead to PR degeneration in humans [ 3 ] ."