IndraLab

Statements

RNF31 binds CYLD and Trim14. 2 / 2
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"CYLD‐deficient mice have less pronounced phenotypes as compared to A20 xref , xref , and the gene is not substantially induced by NF‐κB. Interestingly, CYLD also binds the HOIP PUB and B‐box domains despite lacking a discernible PIM."
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"It was striking that while CYLD was unable to form a stable complex with the PUB domain of HOIP, it instead interacted with the PUB domain in SPATA2 ( xref D, 1K, and xref B)."
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