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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP39 inhibits abnormal cell cycle distribution. 1 / 1

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eidos

"First , we observed that depletion of USP39 contributes to abnormal cell cycle distribution by inducing cell cycle arrest at G2 / M. Moreover , the underlying mechanism of action of USP39 is partly dependent on activation of the p53 pathway , upregulation of p53 and p21 , and downregulation of CDC2 and CyclinB1 [ 29 ] in A549 cells ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...